A new method to predict bleeding and manage blood transfusions after heart surgery
Integrated Coagulation Sensing to Predict Hemorrhage and Guide Transfusions
This study is working on a handy device that helps doctors predict bleeding and manage blood transfusions for patients having heart surgery, aiming to make sure they get the right amount of blood at the right time to improve their recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10204092 on NIH RePORTER |
What this research studies
This research aims to create a point-of-care device that can accurately predict bleeding events and guide blood transfusions for patients undergoing cardiac surgery. By addressing the challenges of coagulopathy, which affects over half of these patients, the study seeks to improve patient outcomes by ensuring timely and appropriate blood component transfusions. The approach involves developing algorithms that can assess coagulation status in real-time, allowing for better management of bleeding risks during and after surgery. This could significantly reduce complications associated with both under- and over-transfusion of blood products.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients scheduled for complex cardiac surgeries who are at risk of bleeding due to coagulation disorders.
Not a fit: Patients who are not undergoing cardiac surgery or those with stable coagulation profiles may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer cardiac surgeries with fewer complications related to bleeding and transfusions.
How similar studies have performed: Previous research has shown promise in developing point-of-care coagulation monitoring tools, indicating potential success for this novel approach.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Nadkarni, Seemantini K — Massachusetts General Hospital
- Study coordinator: Nadkarni, Seemantini K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.