NIH-funded research Sbir 2 grant

A new method to measure muscle health using electrical signals

Official title: Convenient quantification of myopathic change in muscle via electrical impedance myography

Funded at Myolex, INC. · NIH-11112443 · Data updated 2026-11-12

This study is testing a new, easier way to check the health of your muscles using a device called mScan, which could help people with muscle disorders get better care without the hassle of traditional MRI scans.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionMyolex, INC.
NIH-funded
Lab location1 site (Brookline, UNITED STATES)
Project startJune 15, 2024
Project endMay 31, 2026
Funding year2025
Award (this year)$963,608
NIH project number5R44AR083316-02
Project IDNIH-11112443 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with muscle disorders such as muscular dystrophy or those experiencing muscle atrophy due to aging or injury.

Less likely to help

Patients with muscle conditions that do not involve significant changes in muscle composition may not benefit from this research.

What this research studies

This research investigates a novel technique called electrical impedance myography (EIM) to assess muscle condition more conveniently and cost-effectively than traditional MRI. EIM can provide insights into muscle pathology, track disease progression, and monitor responses to therapy without the need for patients to undergo the cumbersome MRI process. The goal is to develop a device, the mScan, that simplifies the analysis of muscle health, making it accessible for both clinical trials and individual patient care. This approach aims to improve the quality of life for patients with muscle disorders by offering a less invasive and more efficient diagnostic tool.

Why it matters

Potential benefit: If successful, this research could provide a more accessible and efficient way for patients to monitor their muscle health and disease progression.

How similar studies have gone: Previous studies have shown that electrical impedance myography can effectively correlate with muscle pathology, indicating potential success for this approach.

Where this research is happening

  • Myolex, INC.
    Brookline, United States
    Active

Researchers

  • Principal investigator: Dickinson, David P. — Myolex, INC.
  • Study coordinator: Dickinson, David P.

Related research

Other NIH-funded projects on the same topics.

  • Electrical impedance measurements to track cancer-related muscle loss

    A first-ever test using a handheld device to measure muscle health in adults with cancer to help diagnose and monitor cancer cachexia.

    NIH research Myolex, INC. · Brookline, UNITED STATES · NIH-11402064

  • Assessing muscle health in older adults using electrical signals

    This study is looking at a new, quick way to check the muscle health of older adults to help spot sarcopenia, which is when people lose muscle strength as they age, using a safe technique that sends small electrical currents through the muscles, so we can better support seniors in staying strong and independent.

    NIH research Myolex, INC. · Brookline, UNITED STATES · NIH-10668482

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.