NIH-funded research R21 grant

A new method to measure fetal oxygen levels during labor

Official title: Interferometric near-infrared spectroscopy for transabdominal fetal oximetry

Funded at University of California at Davis · NIH-11249508 · Data updated 2026-11-12

This study is testing a new, gentle way to check how much oxygen your baby is getting while you're pregnant, using light that shines through your belly, to help doctors make better decisions during labor and possibly reduce the need for C-sections.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis
NIH-funded
Lab location1 site (Davis, United States)
Project startJanuary 1, 2024
Project endDecember 31, 2025
Funding year2025
Award (this year)$227,548
NIH project number5R21HD114014-02
Project IDNIH-11249508 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are pregnant women who are at risk of complications during labor, particularly those facing the possibility of a C-section.

Less likely to help

Patients who are not pregnant or those who are not at risk for complications during labor may not benefit from this research.

What this research studies

This research investigates a noninvasive technique called interferometric near-infrared spectroscopy to measure fetal oxygen saturation through the mother's abdomen. By shining near-infrared light on the maternal abdomen, the method aims to provide real-time data on fetal oxygen levels, which could help obstetricians make informed decisions during labor. The goal is to reduce the reliance on traditional fetal monitoring methods that often lead to unnecessary C-sections due to false-positive results. If successful, this approach could improve outcomes for both mothers and babies during childbirth.

Why it matters

Potential benefit: If successful, this research could significantly reduce the number of unnecessary C-sections, leading to safer childbirth experiences for mothers and infants.

How similar studies have gone: Other research has shown promise in noninvasive fetal monitoring techniques, but this specific approach using interferometric near-infrared spectroscopy is relatively novel.

Where this research is happening

  • University of California at Davis
    Davis, United States
    Active

Researchers

  • Principal investigator: Yang, Weijian — University of California at Davis
  • Study coordinator: Yang, Weijian

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.