A new method to influence decision-making in the brain

A novel technique for selective manipulation of prefrontal computations in economic choice

NIH-funded research Rutgers the State Univ of Nj Newark · NIH-10952602

This study is exploring a new way to gently influence brain activity in a part of the brain that helps with decision-making, specifically looking at how it affects choices about money, and it's designed for researchers interested in understanding how our brains work when we make decisions.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionRutgers the State Univ of Nj Newark NIH-funded
Lab location1 site (Newark, United States)
Project IDNIH-10952602 on NIH RePORTER

What this research studies

This research investigates a novel technique to selectively manipulate neural activity in the prefrontal cortex of primates, which is crucial for understanding decision-making processes. By using multi-channel electrical stimulation, the researchers aim to target specific patterns of neural activity associated with economic choices while minimizing interference with other brain functions. The study will validate this approach through a primate economic decision paradigm, observing how changes in neural activity affect decision-making behavior. This innovative method could provide insights into the neural mechanisms underlying economic choices and mental health disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research would include individuals experiencing decision-making difficulties related to mental health issues.

Not a fit: Patients who do not have decision-making impairments or mental health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for mental health conditions related to decision-making, such as depression and eating disorders.

How similar studies have performed: While this approach is innovative, similar techniques in neuroscience have shown promise in manipulating neural activity to influence behavior.

Where this research is happening

Newark, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DisorderDiseaseEating Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.