A new method to image brain function using light technology
Official title: A transformative method for functional brain imaging with Speckle Contrast Optical Spectroscopy
Funded at Boston University (Charles River Campus) · NIH-10902007 · Data updated 2026-11-12
This study is testing a new, easy-to-use imaging technique to check how well the brain is working by looking at blood flow, especially for people with brain injuries or conditions like Alzheimer's, so we can better understand brain health in everyday situations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $364,842 |
| NIH project number | 5UG3EB034710-02 |
| Project ID | NIH-10902007 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals of all ages, particularly children and adults with acquired brain injuries or degenerative neurological disorders.
✕Less likely to help
Patients with conditions unrelated to brain function or those who do not require monitoring of brain activity may not benefit from this research.
What this research studies
This research focuses on developing a novel imaging technique called speckle contrast optical spectroscopy (SCOS) to monitor brain function non-invasively. By measuring changes in blood flow related to brain activity, this method aims to provide insights into brain health and disease, particularly for patients with brain injuries or neurodegenerative disorders. The approach is designed to be more accessible and effective for populations where traditional imaging methods, like MRI, may be challenging, such as children and individuals with movement. The goal is to create devices that can be used in everyday settings to enhance our understanding of brain function.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment options for patients with brain injuries and neurodegenerative diseases.
How similar studies have gone: Previous research has shown promise in using optical methods for brain imaging, but this specific approach with SCOS is relatively novel and untested.
Where this research is happening
-
Boston University (Charles River Campus)
Boston, United States Active
Researchers
- Principal investigator: Cheng, Xiaojun — Boston University (Charles River Campus)
- Study coordinator: Cheng, Xiaojun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.