A new method to find and test migraine treatments
Official title: A novel platform for the discovery and characterization of migraine therapies
Funded at University of California Los Angeles · NIH-10973532 · Data updated 2026-11-12
This study is testing a new tiny device that can be placed on the skull to keep an eye on brain activity and behavior linked to migraines, helping researchers learn more about what triggers migraines and how different treatments can help.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $455,371 |
| NIH project number | 1R61NS133274-01A1 |
| Project ID | NIH-10973532 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who experience frequent migraines and are seeking new treatment options.
✕Less likely to help
Patients who do not suffer from migraines or have other unrelated neurological conditions may not benefit from this research.
What this research studies
This research focuses on developing a cutting-edge microchip-based system that can be attached to the skull to continuously monitor brain activity and behavior related to migraines. By using this innovative platform, researchers aim to better understand how established migraine triggers affect neurovascular responses and how different therapies can alleviate these symptoms. The study will involve quantifying responses to known migraine triggers and testing both acute and preventive migraine therapies, with findings validated across multiple institutions. This approach seeks to overcome current limitations in animal models used for migraine research.
Why it matters
Potential benefit: If successful, this research could lead to the discovery of more effective treatments for migraine sufferers.
How similar studies have gone: Previous research has shown promise in using advanced monitoring techniques for neurological conditions, suggesting potential success for this novel approach.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Charles, Andrew C — University of California Los Angeles
- Study coordinator: Charles, Andrew C
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.