A new method to detect early signs of Alzheimer's disease using blood biomarkers.
Official title: A Diagnostic Platform for Extracellular Vesicle-Derived Biomarkers - Towards Early Detection of Alzheimer's Disease
Funded at North Carolina Agri & Tech St Univ · NIH-11064789 · Data updated 2026-11-12
This study is working on a new, easy way to spot early signs of Alzheimer's disease using tiny particles from your blood, so that people can get help sooner, even before symptoms show up.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina Agri & Tech St Univ NIH-funded |
| Lab location | 1 site (Greensboro, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $140,738 |
| NIH project number | 5R16GM149496-03 |
| Project ID | NIH-11064789 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for Alzheimer's disease or those in the early stages of cognitive decline.
✕Less likely to help
Patients with advanced Alzheimer's disease or those who do not exhibit any risk factors for the disease may not benefit from this research.
What this research studies
This research focuses on developing a diagnostic platform that utilizes extracellular vesicles derived from blood to identify biomarkers for early detection of Alzheimer's disease. The approach aims to create a non-invasive screening method that can detect Alzheimer's before clinical symptoms appear, allowing for timely interventions. By analyzing these vesicles, the research seeks to overcome the limitations of current diagnostic methods that rely on cerebrospinal fluid. The goal is to facilitate early treatment options that could improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and intervention for Alzheimer's disease, potentially slowing its progression.
How similar studies have gone: Previous research has shown promise in using extracellular vesicles for disease detection, indicating potential success for this novel approach.
Where this research is happening
-
North Carolina Agri & Tech St Univ
Greensboro, United States Active
Researchers
- Principal investigator: Dellinger, Kristen — North Carolina Agri & Tech St Univ
- Study coordinator: Dellinger, Kristen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.