A new method to break large kidney stones using sound waves

Break Wave lithotripsy to fragment large kidney stones

NIH-funded research Sonomotion, INC. · NIH-11066949

This study is testing a new, gentle treatment called burst wave lithotripsy that uses sound waves to break up larger kidney stones (10-20 mm) without surgery, aiming to make the process safer and more effective for people dealing with these stones.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionSonomotion, INC. NIH-funded
Lab location1 site (Emerald Hills, United States)
Project IDNIH-11066949 on NIH RePORTER

What this research studies

This research focuses on developing a noninvasive treatment called burst wave lithotripsy (BWL) to effectively fragment larger kidney stones, specifically those measuring between 10-20 mm. The approach utilizes a specialized ultrasound technology that generates sound waves to break the stones without the need for surgery. The research aims to enhance the safety and effectiveness of this treatment by creating a compact transducer that can deliver the necessary pressure and frequency to achieve optimal results. By testing this innovative method preclinically, the researchers hope to provide a safer alternative to traditional kidney stone surgeries.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from large kidney stones, particularly those between 10-20 mm in diameter.

Not a fit: Patients with kidney stones smaller than 10 mm or those who have other underlying health conditions that complicate treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the need for invasive surgeries and the associated risks for patients with large kidney stones.

How similar studies have performed: Previous research has shown success with similar noninvasive approaches for smaller stones, indicating potential for this novel method to be effective for larger stones as well.

Where this research is happening

Emerald Hills, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.