A new method to analyze tiny particles that may help treat Alzheimer's disease.
Official title: An Ultrasensitive Flow Cytometry System for Multiparametric Analysis of Therapeutic Anti-Aging Extracellular Vesicles
Funded at Kinetic River Corporation · NIH-10921819 · Data updated 2026-11-12
This study is working on a new way to look at tiny particles released by cells, called extracellular vesicles, which could help in treating conditions like Alzheimer's and understanding different diseases better.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kinetic River Corporation NIH-funded |
| Lab location | 1 site (Mountain View, United States) |
| Project start | August 15, 2024 |
| Project end | December 14, 2025 |
| Funding year | 2024 |
| Award (this year) | $356,497 |
| NIH project number | 1R43GM155492-01 |
| Project ID | NIH-10921819 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those at risk of developing neurodegenerative disorders.
✕Less likely to help
Patients with conditions unrelated to neurodegenerative diseases or those not producing extracellular vesicles may not benefit from this research.
What this research studies
This research focuses on developing an advanced flow cytometry system to analyze extracellular vesicles (EVs), which are small particles released by cells. These EVs have potential therapeutic applications for conditions like Alzheimer's disease and can serve as biomarkers for various diseases. The study aims to improve the characterization of EVs by examining their size and molecular content, which is crucial for understanding their functions and therapeutic potential. By utilizing nanoparticle flow cytometry, the research seeks to provide a more efficient and detailed analysis of these vesicles compared to existing methods.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for Alzheimer's disease and better diagnostic tools for neurodegenerative conditions.
How similar studies have gone: Previous research has shown promise in using extracellular vesicles for therapeutic purposes, indicating that this approach could be a significant advancement in the field.
Where this research is happening
-
Kinetic River Corporation
Mountain View, United States Active
Researchers
- Principal investigator: Vacca, Giacomo — Kinetic River Corporation
- Study coordinator: Vacca, Giacomo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.