A new method to analyze individual cells in human tissues.
A platform for scalable spatial single cell genomics
This study is testing a new technology called Slide-tags that helps scientists look closely at individual cells in human tissues to better understand how they work together in both healthy and sick conditions, which could lead to important discoveries about diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11138774 on NIH RePORTER |
What this research studies
This research focuses on developing a groundbreaking technology called Slide-tags, which allows scientists to analyze the genetic and epigenetic information of individual cells while also mapping their locations within human tissues. By examining millions of cells simultaneously, this approach aims to enhance our understanding of how cells interact in both healthy and diseased states. The technology will be compatible with various types of tissue samples, enabling comprehensive profiling that could lead to significant insights into tissue function and disease mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions affecting human tissues, particularly those related to the brain and other complex organ systems.
Not a fit: Patients with isolated genetic disorders that do not involve complex tissue interactions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostics and treatments for a variety of diseases by providing deeper insights into cellular interactions and functions.
How similar studies have performed: Other research has shown promising results using similar single-cell genomic technologies, indicating a strong potential for success in this novel approach.
Where this research is happening
Cambridge, United States
- Broad Institute, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Chen, Fei — Broad Institute, INC.
- Study coordinator: Chen, Fei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.