A new method for testing how drugs are cleared from the body
Hepatic Clearance Chip for Pharmacokinetics
This study is working on a new device that mimics how the human liver processes medications, which could help researchers develop safer and more effective drugs faster, ultimately benefiting patients like you.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Javelin Biotech NIH-funded |
| Lab location | 1 site (Woburn, UNITED STATES) |
| Project ID | NIH-10916498 on NIH RePORTER |
What this research studies
This research focuses on developing a novel hepatic clearance chip that aims to improve drug metabolism and pharmacokinetic testing (DMPK). By creating a more predictive and cost-effective alternative to traditional animal models, this approach seeks to streamline the drug development process. The chip will simulate human liver function, allowing for better understanding of how drugs are processed in the body, which could lead to faster and more reliable results. Patients may benefit from this research as it could lead to safer and more effective medications entering clinical trials sooner.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals involved in drug development or those interested in the pharmaceutical industry's approach to drug testing.
Not a fit: Patients who are not involved in drug development or who do not have a vested interest in pharmaceutical testing may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the time and cost associated with drug development, leading to more effective treatments for patients.
How similar studies have performed: While there have been attempts to improve DMPK testing through in vitro methods, this specific approach using a hepatic clearance chip is relatively novel and has not been widely tested.
Where this research is happening
Woburn, UNITED STATES
- Javelin Biotech — Woburn, United States (Active)
Researchers
- Principal investigator: Cirit, Murat — Javelin Biotech
- Study coordinator: Cirit, Murat
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.