A new method for recording electrical signals in heart cells
An electrophysiology platform that enables robust, scalable and long-term intracellular recording of cardiomyocytes
This study is working on a new way to safely and easily measure the electrical activity of heart cells, which could help researchers better understand how the heart works and how different medications affect it, ultimately leading to improved treatments for heart conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10881996 on NIH RePORTER |
What this research studies
This research focuses on developing an innovative platform for recording the electrical activity of heart cells, known as cardiomyocytes. By utilizing advanced nanoelectrode arrays, the project aims to enable non-invasive and high-throughput measurements of intracellular action potentials, which are critical for understanding heart function and drug effects. This approach seeks to overcome the limitations of traditional methods that are invasive and time-consuming, making it easier to study heart cells derived from stem cells. The goal is to improve drug screening and characterization of heart cell behavior, ultimately leading to better treatments for heart conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with heart conditions or those interested in the effects of drugs on heart function.
Not a fit: Patients with non-cardiac conditions or those who do not have access to the required technology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for heart diseases by improving our understanding of heart cell behavior and drug interactions.
How similar studies have performed: Other research has shown promise with similar nanoelectrode technologies, indicating potential for success in this innovative approach.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Cui, Bianxiao — Stanford University
- Study coordinator: Cui, Bianxiao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.