A new method for monitoring blood and kidney health in critically ill children
Official title: A Low Blood Volume Platform for Recurrent Anticoagulation and Kidney Monitoring during Continuous Renal Replacement Therapy in Critically Ill Children
Funded at Baebies, INC. · NIH-10863941 · Data updated 2026-11-12
This study is testing a new way to check blood thinning and kidney health in critically ill kids who need special kidney treatment, using less blood for tests to help keep them safe and healthy.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baebies, INC. NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | May 23, 2022 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $948,080 |
| NIH project number | 5R44HL162151-03 |
| Project ID | NIH-10863941 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include critically ill children, particularly newborns and small children under 10 kg, who require continuous renal replacement therapy.
✕Less likely to help
Patients who are not critically ill or do not require renal replacement therapy may not benefit from this research.
What this research studies
This research focuses on developing a low blood volume platform that allows for frequent monitoring of anticoagulation and kidney function in critically ill children undergoing continuous renal replacement therapy (CRRT). The approach aims to reduce the amount of blood needed for testing, which is particularly important for newborns and small children who are at risk of anemia from frequent blood draws. By using this innovative platform, healthcare providers can more effectively manage anticoagulant therapy and monitor kidney health, potentially improving outcomes for these vulnerable patients.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of anemia in critically ill children while improving the management of their kidney health during treatment.
How similar studies have gone: Other research has shown promise in developing low-volume blood testing methods, indicating that this approach could be viable and beneficial.
Where this research is happening
-
Baebies, INC.
Durham, United States Active
Researchers
- Principal investigator: Pamula, Vamsee K. — Baebies, INC.
- Study coordinator: Pamula, Vamsee K.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.