A new method for isolating and tracking cells using advanced imaging technology
Official title: An Affordable and Versatile Two-Dimensional Cell Isolation and Tracking Platform Based on Image Machine Learning and Maskless Photolithography Single Cell Encapsulation
Funded at Lehigh University · NIH-10684026 · Data updated 2026-11-12
This study is working on a new, friendly tool that helps scientists sort and track different types of cells, including delicate ones like stem cells, using smart technology, so smaller labs can do their work more easily and accurately.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lehigh University NIH-funded |
| Lab location | 1 site (Bethlehem, United States) |
| Project start | September 1, 2022 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $237,163 |
| NIH project number | 5R21EB033102-02 |
| Project ID | NIH-10684026 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals requiring stem cell therapies or those with conditions that could benefit from precise cell isolation and tracking.
✕Less likely to help
Patients who do not require cell-based therapies or those whose conditions do not involve cell isolation may not benefit from this research.
What this research studies
This research focuses on developing an innovative platform for isolating and tracking cells using machine learning and advanced photolithography techniques. It aims to create a more efficient and affordable cell sorting system that can handle various cell types, including sensitive cells like stem cells. By utilizing real-time imaging and acoustic fields, the platform seeks to improve the accuracy and speed of cell sorting while minimizing damage to fragile cells. This could significantly enhance the capabilities of small laboratories that require effective cell sorting solutions.
Why it matters
Potential benefit: If successful, this research could provide patients with improved access to advanced cell therapies and treatments by enabling better isolation of critical cell types.
How similar studies have gone: Other research has shown promise in using machine learning and innovative sorting techniques for cell isolation, indicating that this approach could lead to significant advancements.
Where this research is happening
-
Lehigh University
Bethlehem, United States Active
Researchers
- Principal investigator: Berdichevsky, Yevgeny — Lehigh University
- Study coordinator: Berdichevsky, Yevgeny
Related research
Other NIH-funded projects on the same topics.
-
Integrating data-driven models to understand tissue function and degeneration
Aims to build a digital twin of human tissues to better understand how tissue heterogeneity and cell signaling affect growth, remodeling, and the risk of aneurysm-related tissue degeneration.
-
Computational tools to study how biological molecules interact
A project to create and improve software that helps scientists model and predict how biological molecules bind and work together in living systems, with a focus on tools used by many researchers.
-
Selective vulnerability of dopamine neurons in fruit flies
Researchers are studying why certain dopamine-producing brain cells in fruit flies are more likely to fail in neurodegenerative conditions, with the goal of informing protective strategies for people.
-
Nuclear Envelope Dynamics in Meiotic Quality Control
A researcher at Lehigh University is exploring how eggs and sperm maintain quality during meiosis in a worm model to prevent chromosome errors that can cause birth defects.
-
Pennsylvania asthma-COPD syndromic surveillance for cleaner air and healthier kids
A Pennsylvanian health project is building a real-time warning system to help doctors and families spot spikes in asthma and COPD risks related to air pollution and smoke.
-
Impact of Displacement on Aging Immigrant Mental Health and Interventions
A project with Lehigh University will explore how past displacement affects the mental health of older Bhutanese American immigrants and develop ideas for supportive interventions.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.