A new method for analyzing proteins using fewer samples
Official title: Accessible and Robust High-Throughput Western Blotting for Small Sample Sizes
Funded at Blotting Innovations, LLC · NIH-10545990 · Data updated 2026-11-12
This study is testing a new, faster way to analyze proteins that could help labs work more efficiently and accurately, which might lead to quicker and better diagnoses for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Blotting Innovations, LLC NIH-funded |
| Lab location | 1 site (Central, United States) |
| Project start | September 22, 2022 |
| Project end | September 21, 2025 |
| Funding year | 2022 |
| Award (this year) | $288,767 |
| NIH project number | 1R41GM148112-01 |
| Project ID | NIH-10545990 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that require protein analysis for diagnosis or treatment monitoring.
✕Less likely to help
Patients who do not require protein analysis or whose conditions are unrelated to protein biomarkers may not benefit from this research.
What this research studies
This research focuses on developing a high-throughput technique called mesowestern for analyzing proteins through western blotting. The mesowestern method allows for the analysis of over 300 samples simultaneously, significantly increasing efficiency while requiring much smaller sample sizes than traditional methods. By utilizing affordable and user-friendly technology, this approach aims to make protein analysis more accessible to various laboratories. Patients may benefit indirectly as this technique could lead to faster and more accurate diagnostics in biomedical research.
Why it matters
Potential benefit: If successful, this research could enhance the speed and accuracy of protein analysis, leading to improved diagnostic capabilities for various medical conditions.
How similar studies have gone: Previous research has shown success with high-throughput protein analysis methods, indicating a promising potential for this novel approach.
Where this research is happening
-
Blotting Innovations, LLC
Central, United States Active
Researchers
- Principal investigator: Birtwistle, Marc R. — Blotting Innovations, LLC
- Study coordinator: Birtwistle, Marc R.
Related research
Other NIH-funded projects on the same topics.
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Developing a new gel and membrane system for better protein analysis
This study is working on a new product that makes it easier and more reliable for scientists to find specific proteins in samples, which can help improve research that benefits patients like you.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.