A new method for analyzing individual cells to understand their differences and responses to diseases
Official title: A novel flexible approach for high-throughput single-cell phenotyping and genotyping
Funded at Flexomics LLC · NIH-11032035 · Data updated 2026-11-12
This study is exploring a new way to look at individual cells to understand how they work and respond to diseases, which could help find better treatments for patients like you.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Flexomics LLC NIH-funded |
| Lab location | 1 site (Waltham, United States) |
| Project start | February 9, 2024 |
| Project end | January 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $1,040,098 |
| NIH project number | 5R44HG013448-02 |
| Project ID | NIH-11032035 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve significant cellular heterogeneity, such as cancer or autoimmune diseases.
✕Less likely to help
Patients with stable, well-characterized conditions that do not involve complex cellular interactions may not benefit from this research.
What this research studies
This research focuses on developing an innovative platform that combines imaging and sequencing technologies to analyze individual cells. By isolating and examining thousands of cells simultaneously, the study aims to uncover how cells differ from one another and how they respond to various diseases. Patients may benefit from this research as it seeks to identify cells with therapeutic potential, which could lead to more effective treatments. The approach involves advanced techniques such as high-density picowell arrays and nucleic-acid barcoding to gather comprehensive data on cell behavior and characteristics.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding cellular responses to diseases, ultimately improving treatment options for patients.
How similar studies have gone: Previous research has shown promise in using combined imaging and sequencing techniques for single-cell analysis, indicating potential for success in this novel approach.
Where this research is happening
-
Flexomics LLC
Waltham, United States Active
Researchers
- Principal investigator: Soumillon, Magali — Flexomics LLC
- Study coordinator: Soumillon, Magali
Related research
Other NIH-funded projects on the same topics.
-
Identifying T-Cell Receptors to Improve Cancer Immunotherapy
This study is working on a new way to find and understand special immune cells that can target unique markers on cancer cells, with the hope of creating better and more personalized treatments for cancer patients.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.