A new method for analyzing DNA changes in cancer patients
A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research
This study is working on a new, easier way to check for cancer by looking at DNA from your blood, which could help doctors diagnose and monitor cancer without needing to do more invasive tissue biopsies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10891661 on NIH RePORTER |
What this research studies
This research focuses on developing a highly sensitive technique for analyzing DNA methylation patterns in cancer patients. By using circulating cell-free DNA from blood samples, the study aims to create a less invasive and more efficient way to diagnose and monitor cancer. The approach seeks to overcome the limitations of traditional tissue biopsies, which often do not provide enough material for comprehensive analysis. If successful, this method could significantly enhance cancer diagnostics and patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with cancer who are undergoing treatment or monitoring.
Not a fit: Patients who are not diagnosed with cancer or those who do not have sufficient circulating cell-free DNA may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and less invasive cancer diagnostics, improving patient outcomes.
How similar studies have performed: Other research has shown promise in using similar approaches for cancer diagnostics, indicating potential for success in this novel method.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Chiu, Brian C-H — University of Chicago
- Study coordinator: Chiu, Brian C-H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.