A new material to help rebuild soft tissues in the face
Biostimulatory nanofiber-hydrogel composite for soft tissue remodeling
['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-11019800
This study is testing a new material made from tiny fibers and a gel that helps heal and rebuild soft tissue in the face after surgery, making it easier for your body to grow back healthy tissue and possibly reducing the number of surgeries you might need.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11019800 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a biostimulatory nanofiber-hydrogel composite that can restore soft tissue in craniofacial reconstructive surgery. The approach aims to create a solution that not only fills the tissue loss but also promotes natural tissue growth and remodeling over time. By using a combination of polyester nanofibers and hyaluronic acid, the material encourages the infiltration of host cells and improves the healing process. This innovative method seeks to reduce the need for multiple surgeries and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with craniofacial soft tissue losses due to congenital conditions, trauma, or surgery.
Not a fit: Patients with conditions that do not involve soft tissue loss or those who are not candidates for reconstructive surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more effective and less invasive option for patients needing soft tissue reconstruction in the face.
How similar studies have performed: Previous research has shown promise in using biomaterials for tissue engineering, indicating potential success for this novel approach.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: REDDY, SASHANK K — JOHNS HOPKINS UNIVERSITY
- Study coordinator: REDDY, SASHANK K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.