A new lab-on-a-chip system for precise sensing and manipulation of biological systems
Official title: Optoeletronic Micro-Gadget (OMG): a Photoelectrochemistry-Enabled Multi-Utility Lab-on-a-Chip System for Precise and Localized Sensing and Actuation
Funded at Ohio State University · NIH-11140540 · Data updated 2026-11-12
This study is working on a new, tiny device that can help doctors detect important signs of health and even influence how cells behave, which could lead to better ways to diagnose and treat patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | August 1, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $186,341 |
| NIH project number | 5R21EB035153-02 |
| Project ID | NIH-11140540 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that require precise biomarker detection or localized treatment interventions.
✕Less likely to help
Patients with conditions that do not involve complex biological systems or require broad-spectrum treatments may not benefit from this research.
What this research studies
This research focuses on developing an innovative lab-on-a-chip (LOC) system that utilizes photoelectrochemistry for precise and localized sensing and actuation of complex biological systems. By overcoming the limitations of traditional electrode designs, this project aims to create a flexible and adaptable platform that can detect biomarkers and manipulate cellular processes more effectively. Patients may benefit from advancements in diagnostics and treatment options that arise from improved biosensing technologies. The approach involves integrating advanced electrochemical techniques to enhance the resolution and functionality of the LOC system.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and targeted therapies for various medical conditions.
How similar studies have gone: Similar research has shown promise in enhancing biosensing technologies, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Li, Jinghua — Ohio State University
- Study coordinator: Li, Jinghua
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.