A new instrument to understand how immune cells work
Dynamic single-cell analysis instrument to evaluate immune cell function
This project is developing a special instrument that uses advanced imaging and AI to watch individual immune cells in action, helping us understand how they fight diseases like cancer.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cellchorus INC. NIH-funded |
| Lab location | 1 site (Houston, UNITED STATES) |
| Project ID | NIH-11323428 on NIH RePORTER |
What this research studies
This project focuses on building Chronos, a dedicated instrument designed to work with the CellChorus TIMING platform. The TIMING platform allows scientists to place cells in tiny wells and then rapidly take time-lapse images over several hours. These images are then analyzed by AI to understand how cells behave, which is especially useful for studying immune cells like CAR T cells. The goal is to make it easier for researchers to use this technology to identify the most effective immune cells for treatments.
Who could benefit from this research
Good fit: This project is developing a research tool and does not directly involve patient participation at this stage, but future applications could benefit patients receiving cell-based therapies.
Not a fit: Patients not undergoing or considering cell-based immune therapies would not directly benefit from this specific instrument development.
Why it matters
Potential benefit: If successful, this instrument could help identify more effective immune cells for therapies, potentially leading to better treatments for patients with conditions like cancer.
How similar studies have performed: The underlying TIMING technology has shown promising results in identifying potent CAR T cells, as highlighted by a recent publication in Nature Cancer.
Where this research is happening
Houston, UNITED STATES
- Cellchorus INC. — Houston, United States (Active)
Researchers
- Principal investigator: Cooper, Laurence J.n. — Cellchorus INC.
- Study coordinator: Cooper, Laurence J.n.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.