A new instrument for measuring biomolecule mass in solution
Official title: Refeyn TwoMP Mass Photometer
Funded at Rutgers Biomedical and Health Sciences · NIH-11101164 · Data updated 2026-11-12
This study is about getting a special tool that helps scientists measure the weight of proteins in a solution without using labels, making it easier for researchers, including those supported by the NIH, to understand how proteins interact and work together.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project start | May 15, 2025 |
| Project end | May 14, 2026 |
| Funding year | 2025 |
| Award (this year) | $254,355 |
| NIH project number | 1S10OD038160-01 |
| Project ID | NIH-11101164 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals involved in studies of protein interactions and those requiring advanced biochemical analysis.
✕Less likely to help
Patients not involved in research related to protein interactions or structural biology may not receive direct benefits from this research.
What this research studies
This research aims to acquire a Refeyn Two-MP Mass Photometer, which will allow for precise, label-free measurement of the mass of biomolecules in solution. By enabling the quantification of protein interactions and determining their stoichiometry, this instrument will enhance the ability to conduct structural and biochemical studies. It will be housed at Rutgers University's Mass Spectrometry core facility, making it accessible to various researchers, including those funded by NIH. The technology promises to improve the efficiency of functional assays and macromolecular assembly studies.
Why it matters
Potential benefit: If successful, this research could significantly advance our understanding of biomolecular interactions and improve the development of therapeutic strategies.
How similar studies have gone: Other research has successfully utilized similar mass photometry techniques, indicating a promising potential for this novel instrument.
Where this research is happening
-
Rutgers Biomedical and Health Sciences
Newark, United States Active
Researchers
- Principal investigator: Patel, Smita S — Rutgers Biomedical and Health Sciences
- Study coordinator: Patel, Smita S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.