NIH-funded research R01 grant

A new injectable method for contraception and HIV prevention.

Official title: Ultra-Long-Acting Polymeric Injectable Multi-Purpose Prevention Technology for Contraception and HIV Prevention

Funded at Univ of North Carolina Chapel Hill · NIH-11064826 · Data updated 2026-11-12

This study is working on a new long-lasting injection that helps women prevent both pregnancy and HIV, giving them more control over their health without needing to worry about taking a pill every day.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startApril 13, 2021
Project endMarch 31, 2026
Funding year2025
Award (this year)$720,390
NIH project number5R01AI162246-05
Project IDNIH-11064826 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women who are at risk of HIV infection and are seeking effective contraception methods.

Less likely to help

Patients who are not at risk of HIV or do not require contraception may not benefit from this research.

What this research studies

This research focuses on developing a long-acting injectable formulation that can provide both contraception and HIV prevention, specifically designed for female use. The approach aims to create a multi-purpose prevention technology (MPT) that can be administered without the need for immediate sexual activity, enhancing women's control over their reproductive health. The methodology involves using innovative nano-formulations that release medication over extended periods, ensuring high efficacy and patient compliance. The study builds on existing data to overcome current limitations in combining multiple drugs into a single injection.

Why it matters

Potential benefit: If successful, this research could provide women with a reliable and convenient method for preventing both unplanned pregnancies and HIV infection.

How similar studies have gone: Previous research has shown promise with long-acting injectable formulations for HIV prevention, but this specific multi-purpose approach is novel.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Benhabbour, Soumya Rahima — Univ of North Carolina Chapel Hill
  • Study coordinator: Benhabbour, Soumya Rahima

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.