A new injectable electrode to improve treatment for Overactive Bladder
Official title: An Injectable Electrode to Better Isolate the Posterior Tibial Nerve to Treat OAB
Funded at University of Wisconsin-Madison · NIH-10943254 · Data updated 2026-11-12
This study is testing a new injectable device that aims to better target the nerve responsible for Overactive Bladder, which could help improve treatment for patients who haven't had success with current options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | September 18, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $628,012 |
| NIH project number | 1R01NS138422-01 |
| Project ID | NIH-10943254 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing refractory Overactive Bladder, particularly those who have not found relief from standard treatments.
✕Less likely to help
Patients with mild OAB symptoms or those who have not been diagnosed with Overactive Bladder may not benefit from this research.
What this research studies
This research focuses on developing a novel injectable electrode designed to better isolate the posterior tibial nerve, which is crucial for treating Overactive Bladder (OAB). The approach aims to enhance the effectiveness of nerve stimulation therapies by ensuring more precise targeting of the nerve, potentially reducing side effects and improving patient outcomes. The study will involve engineering a minimally invasive device made from two passive materials, which will be validated and optimized through clinical testing. Patients suffering from OAB may find this new treatment option beneficial, especially those who have not responded well to existing therapies.
Why it matters
Potential benefit: If successful, this research could provide a more effective and less invasive treatment option for patients suffering from Overactive Bladder.
How similar studies have gone: Previous research has shown promise with nerve stimulation therapies for OAB, but this approach aims to improve upon existing methods, making it a novel endeavor.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Ludwig, Kip a — University of Wisconsin-Madison
- Study coordinator: Ludwig, Kip a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.