A new injectable electrode to improve treatment for Overactive Bladder

An Injectable Electrode to Better Isolate the Posterior Tibial Nerve to Treat OAB

NIH-funded research University of Wisconsin-Madison · NIH-10943254

This study is testing a new injectable device that aims to better target the nerve responsible for Overactive Bladder, which could help improve treatment for patients who haven't had success with current options.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison NIH-funded
Lab location1 site (Madison, United States)
Project IDNIH-10943254 on NIH RePORTER

What this research studies

This research focuses on developing a novel injectable electrode designed to better isolate the posterior tibial nerve, which is crucial for treating Overactive Bladder (OAB). The approach aims to enhance the effectiveness of nerve stimulation therapies by ensuring more precise targeting of the nerve, potentially reducing side effects and improving patient outcomes. The study will involve engineering a minimally invasive device made from two passive materials, which will be validated and optimized through clinical testing. Patients suffering from OAB may find this new treatment option beneficial, especially those who have not responded well to existing therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing refractory Overactive Bladder, particularly those who have not found relief from standard treatments.

Not a fit: Patients with mild OAB symptoms or those who have not been diagnosed with Overactive Bladder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a more effective and less invasive treatment option for patients suffering from Overactive Bladder.

How similar studies have performed: Previous research has shown promise with nerve stimulation therapies for OAB, but this approach aims to improve upon existing methods, making it a novel endeavor.

Where this research is happening

Madison, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.