A new injectable capsule that releases medication over time
Official title: Predictive Drug Release from a Tunable Injectable Capsule
Funded at Ohio State University · NIH-10881664 · Data updated 2026-11-12
This study is working on a new type of tiny capsule that can slowly release medicine for people with chronic conditions like wet age-related macular degeneration, so they won't have to get injections as often, making treatment easier and more comfortable.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | July 5, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $489,858 |
| NIH project number | 5R01EB032870-02 |
| Project ID | NIH-10881664 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic conditions that require frequent injections, particularly those with wet age-related macular degeneration.
✕Less likely to help
Patients who do not require injectable treatments or those with conditions that are not targeted by this research may not benefit.
What this research studies
This research focuses on developing a biodegradable microcapsule that can deliver medications for chronic conditions, such as wet age-related macular degeneration, over an extended period of up to 12 months. By reducing the need for frequent injections, the project aims to enhance patient comfort and treatment adherence while maintaining therapeutic efficacy. The approach combines theoretical modeling with laboratory studies to optimize the capsule's design and predict how the medication will be released. Patients may benefit from a more convenient and less invasive treatment option.
Why it matters
Potential benefit: If successful, this research could significantly reduce the frequency of injections needed for chronic disease management, improving patient quality of life.
How similar studies have gone: Previous research has shown promise in using sustained-release delivery systems for medications, indicating potential success for this novel approach.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Swindle-Reilly, Katelyn E — Ohio State University
- Study coordinator: Swindle-Reilly, Katelyn E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.