A new injectable capsule for long-lasting medicine delivery
Predictive Drug Release from a Tunable Injectable Capsule
This project is developing a new type of injectable capsule that can release medicine slowly over a long time for people with chronic conditions like wet age-related macular degeneration.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-11140464 on NIH RePORTER |
What this research studies
Many people with chronic conditions need frequent injections, which can be uncomfortable, costly, and lead to missed treatments. This project aims to create a special, tiny capsule that can be injected and then slowly release medicine for up to a year or more. We are combining computer models with lab and animal tests to make sure the capsule works well and releases the right amount of medicine. The goal is to make treatments more convenient and effective, reducing the need for frequent visits and improving overall quality of life.
Who could benefit from this research
Good fit: This research is relevant for patients with chronic conditions, such as wet age-related macular degeneration, who currently require frequent injections for their treatment.
Not a fit: Patients whose conditions do not require frequent injectable medications or those who prefer current treatment methods may not directly benefit from this specific delivery system.
Why it matters
Potential benefit: If successful, this new delivery system could significantly reduce the number of injections needed for chronic conditions, improving patient comfort and treatment adherence.
How similar studies have performed: While sustained-release technologies exist, this project focuses on a novel tunable, injectable, biodegradable microcapsule designed for very long-term release (12+ months) of various therapeutics.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Swindle-Reilly, Katelyn E — Ohio State University
- Study coordinator: Swindle-Reilly, Katelyn E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.