A new inhaled treatment for opioid use disorder

A novel inhaled dry powder psychoplastogenic formulation for treating persons with opioid use disorder

NIH-funded research Quench Medical, INC. · NIH-10916801

This study is testing a new inhaled powder that uses a special compound to help people with opioid use disorder feel better and improve their brain's ability to change, and it's designed for those looking for new ways to manage their addiction.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionQuench Medical, INC. NIH-funded
Lab location1 site (Saint Paul, United States)
Project IDNIH-10916801 on NIH RePORTER

What this research studies

This research investigates a novel inhaled dry powder formulation aimed at treating opioid use disorder (OUD) by utilizing psychoplastogenic compounds that promote neural plasticity. The approach focuses on the inhalation of a specific compound, 5-MeO-DMT, which has shown potential anti-addictive effects. The study aims to determine the optimal dosing strategy and evaluate the efficacy of this treatment in reducing symptoms associated with OUD. Patients will be monitored for improvements in their condition and overall well-being.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorder who are seeking alternative treatment options.

Not a fit: Patients who are not diagnosed with opioid use disorder or those who have not responded to other treatment modalities may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for individuals struggling with opioid use disorder.

How similar studies have performed: While the use of psychoplastogenic compounds is a relatively novel approach, preliminary evidence suggests potential success in treating similar substance use disorders.

Where this research is happening

Saint Paul, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.