A new implant to prevent HIV infection with less frequent dosing
A Bioresorbable Subdermal Implant for Sustained Delivery of a Novel Maturation Inhibitor to Prevent HIV Infection
This study is testing a new implant that slowly releases a special medicine to help prevent HIV, making it easier for people to stay protected without having to take a pill every day or month.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oak Crest Institute of Science NIH-funded |
| Lab location | 1 site (Monrovia, United States) |
| Project ID | NIH-10892211 on NIH RePORTER |
What this research studies
This research focuses on developing a bioresorbable subdermal implant that delivers a novel drug to prevent HIV infection. The implant aims to improve adherence to HIV prevention methods by providing long-lasting protection without the need for daily or monthly dosing. The approach involves a detailed formulation development process, including design, fabrication, and testing in animal models to ensure safety and efficacy. Patients will benefit from a more convenient and effective method of HIV prevention.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at high risk of HIV infection who may benefit from a long-acting prevention method.
Not a fit: Patients who are already HIV positive or those who do not have risk factors for HIV infection may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a long-lasting and effective method for preventing HIV infection, reducing the burden of daily medication adherence.
How similar studies have performed: Other research has shown promise with long-acting drug delivery systems for HIV prevention, indicating potential for success with this novel approach.
Where this research is happening
Monrovia, United States
- Oak Crest Institute of Science — Monrovia, United States (Active)
Researchers
- Principal investigator: Moss, John a — Oak Crest Institute of Science
- Study coordinator: Moss, John a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.