A new implant for replacing damaged knee cartilage

Efficacy of MeniscoFix for Sub-Total Meniscal Replacement: A Comprehensive Approach in Cadaver Knees and an Ovine Surgical Model

NIH-funded research Novopedics, INC. · NIH-11185503

This project is creating a new implant called MeniscoFix to replace damaged knee cartilage and prevent long-term joint problems.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionNovopedics, INC. NIH-funded
Lab location1 site (Princeton, UNITED STATES)
Project IDNIH-11185503 on NIH RePORTER

What this research studies

Many people experience knee cartilage injuries, often leading to surgery that removes the damaged tissue. While this helps short-term, it can change how the knee works and lead to pain and arthritis later on. Our team is developing MeniscoFix, an implant designed to take the place of the damaged cartilage. This implant is designed to be slowly absorbed by the body while new, healthy tissue grows in its place, helping to protect the knee joint. We are testing how well MeniscoFix works in human cadaver knees and in a long-term animal model to understand its effectiveness and how it interacts with the knee.

Who could benefit from this research

Good fit: This research is for patients who have experienced meniscal injuries and are at risk for or currently suffer from post-meniscectomy syndrome or post-traumatic osteoarthritis.

Not a fit: Patients without meniscal injuries or those whose knee problems are not related to cartilage damage may not receive direct benefit from this specific implant.

Why it matters

Potential benefit: If successful, this implant could offer a lasting solution for meniscal injuries, potentially preventing future pain and the development of osteoarthritis.

How similar studies have performed: This project is developing a novel load-bearing meniscal replacement implant, building on the need for improved solutions beyond traditional meniscectomy.

Where this research is happening

Princeton, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.