A new implant for long-term HIV treatment

Ultra-long-acting Biodegradable and Tunable Polymeric Solid Implant for HIV Treatment Maintenance

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10885173

This study is looking to create a special implant that slowly releases HIV medication over a long time, so people don’t have to take daily pills, making it easier for them to stick to their treatment.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10885173 on NIH RePORTER

What this research studies

This research focuses on developing a biodegradable and tunable polymeric solid implant that can provide ultra-long-acting treatment for HIV. The goal is to create a solution that reduces the need for daily medication, thereby improving adherence among patients. By addressing the barriers to consistent treatment, this approach aims to enhance the effectiveness of HIV therapy and reduce the incidence of drug resistance. The research will involve testing the implant's safety and efficacy in delivering antiretroviral drugs over an extended period.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are living with HIV and face challenges with daily medication adherence.

Not a fit: Patients who are not living with HIV or those who do not have access to HIV treatment will not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve treatment adherence for individuals living with HIV, leading to better health outcomes.

How similar studies have performed: Similar research has shown promise in developing long-acting treatments for chronic conditions, indicating potential for success in this novel approach.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.