NIH-funded research R21 grant

A new imaging system to identify tumors in the pancreas and digestive system.

Official title: Geles: A Novel Imaging Informatics System for Generalizable Lesion Identification in Neuroendocrine Tumors

Funded at University of Colorado Denver · NIH-10740578 · Data updated 2026-11-12

This study is working on a new computer system that uses advanced imaging technology to help doctors find and measure gastroenteropancreatic neuroendocrine tumors more accurately, so patients can get better treatment options and care.

More Neuroendocrine Tumors research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startSeptember 19, 2023
Project endAugust 31, 2025
Funding year2023
Award (this year)$388,467
NIH project number1R21CA274487-01A1
Project IDNIH-10740578 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with gastroenteropancreatic neuroendocrine tumors who require accurate assessment of their disease.

Less likely to help

Patients with neuroendocrine tumors that do not express somatostatin receptor subtype 2 may not benefit from this research.

What this research studies

This research focuses on improving the detection of gastroenteropancreatic neuroendocrine tumors (GEP-NETs), which are often diagnosed at advanced stages. The project aims to develop an automated imaging informatics system that utilizes deep learning to enhance the identification and quantification of these tumors using advanced PET/CT imaging techniques. By addressing the challenges of dataset shifts, the research seeks to create a more reliable tool for assessing tumor burden, which is crucial for developing effective treatment strategies. Patients may benefit from more accurate monitoring of their disease, leading to better-informed treatment decisions.

Why it matters

Potential benefit: If successful, this research could lead to improved detection and monitoring of neuroendocrine tumors, enhancing treatment outcomes for patients.

How similar studies have gone: Other research has shown promise in using deep learning for automated lesion detection, but this specific approach addressing dataset shifts is relatively novel.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Xing, Fuyong — University of Colorado Denver
  • Study coordinator: Xing, Fuyong

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.