A new imaging platform to enhance bioluminescence imaging for studying diseases in small animals
Official title: A modular bioluminescence imaging platform using a novel multi-aperture method
Funded at In Vivo Analytics, INC. · NIH-11007824 · Data updated 2026-11-12
This study is working on a new imaging tool that helps scientists see what's happening inside small animals with diseases like cancer, making it easier to understand and study these conditions better.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | In Vivo Analytics, INC. NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 2, 2024 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $299,896 |
| NIH project number | 1R44MH140129-01 |
| Project ID | NIH-11007824 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that are being studied in small animal models, such as cancer or infectious diseases.
✕Less likely to help
Patients who do not have conditions relevant to the small animal models being used in this research may not receive any benefit.
What this research studies
This research focuses on developing a modular bioluminescence imaging platform that improves the ability to visualize biological processes in small animal models of human diseases. The approach involves a novel multi-aperture method that enhances imaging sensitivity and allows for multi-view imaging and 3D tomography. By addressing current limitations in photon detection and anatomical information, this platform aims to provide more accurate and reproducible data for various preclinical applications, including cancer and infectious disease research.
Why it matters
Potential benefit: If successful, this research could lead to more effective preclinical studies, ultimately improving the understanding and treatment of human diseases.
How similar studies have gone: Other research has shown success with similar imaging techniques, indicating a promising avenue for enhancing preclinical studies.
Where this research is happening
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In Vivo Analytics, INC.
New York, United States Active
Researchers
- Principal investigator: Klose, Alexander D. — In Vivo Analytics, INC.
- Study coordinator: Klose, Alexander D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.