A new hydrogel for delivering microRNAs to help heal the heart after injury
Injectable Carbon Nanotube-Functionalized Hydrogel for miRNA Delivery
This study is testing a new gel that can be injected into the heart to help it heal after a heart attack by delivering tiny molecules that support recovery, and it could offer a safer and more effective way for patients to bounce back from heart injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10854889 on NIH RePORTER |
What this research studies
This research focuses on developing an injectable hydrogel that uses carbon nanotubes to deliver microRNAs (miRNAs) directly to the heart. The hydrogel is designed to transition from a liquid to a gel at body temperature, allowing for targeted and effective delivery of miRNAs that promote heart regeneration after a heart attack. By comparing this new method to existing delivery systems, the research aims to demonstrate improved safety and effectiveness in promoting heart healing. Patients may benefit from this innovative approach to enhance recovery from cardiac injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have experienced a myocardial infarction and are seeking advanced treatment options for heart regeneration.
Not a fit: Patients with conditions unrelated to cardiac health or those who have not experienced a heart attack may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer and more effective treatment option for patients recovering from heart injuries.
How similar studies have performed: Other research has shown promise in using innovative delivery systems for miRNAs, but this specific approach with carbon nanotube-functionalized hydrogels is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Pena Castellanos, Brisa Marisol — University of Colorado Denver
- Study coordinator: Pena Castellanos, Brisa Marisol
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.