A new heart valve graft for children with congenital heart disease

Pulmonary Valved Graft with Regeneration Potential for Pediatric Patients

NIH-funded research Annoviant, INC · NIH-11060870

This study is looking at a new type of heart valve that can grow with kids who have heart defects, aiming to make their surgeries safer and help them heal better.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionAnnoviant, INC NIH-funded
Lab location1 site (Alpharetta, United States)
Project IDNIH-11060870 on NIH RePORTER

What this research studies

This research focuses on developing a pulmonary valved graft that has the potential to regenerate for pediatric patients suffering from congenital heart diseases (CHD). The approach involves using innovative materials that can improve blood flow and reduce complications associated with traditional grafts. By studying the effectiveness of these grafts in a controlled setting, the research aims to provide a safer and more effective solution for children with heart defects. Patients may be monitored for their recovery and the long-term performance of the grafts.

Who could benefit from this research

Good fit: Ideal candidates for this research are pediatric patients diagnosed with congenital heart diseases that require surgical intervention.

Not a fit: Patients with congenital heart diseases who are not candidates for surgical intervention or those with other unrelated health issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved surgical outcomes and quality of life for children with congenital heart defects.

How similar studies have performed: Previous research has shown promise in using innovative graft materials for heart surgeries, indicating potential for success in this novel approach.

Where this research is happening

Alpharetta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.