A new heart support device for babies and infants with heart failure

Development of the Inspired Therapeutics NeoMate Mechanical Circulatory Support System for Neonates and Infants

NIH-funded research Inspired Therapeutics, LLC · NIH-10845690

This project is creating a new mechanical heart support device called NeoMate specifically for very young children and infants who have heart failure.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionInspired Therapeutics, LLC NIH-funded
Lab location1 site (Charlottesville, UNITED STATES)
Project IDNIH-10845690 on NIH RePORTER

What this research studies

Many babies and infants with heart failure are too small for existing heart support devices, leading to limited options while they wait for a heart transplant. This project aims to complete the design and testing of the NeoMate, a compact device that can help their hearts pump blood for up to 30 days. We are using advanced computer modeling to predict how the device will work and building the pump and its control system. The goal is to provide a much-needed solution for these tiny patients.

Who could benefit from this research

Good fit: This device is being developed for neonates and infants under 10 kilograms who are experiencing heart failure.

Not a fit: Older children or adults with heart failure, or those without heart failure, would not be candidates for this specific device.

Why it matters

Potential benefit: If successful, this device could offer a life-saving option for neonates and infants with heart failure, supporting them until a heart transplant becomes available.

How similar studies have performed: Initial prototype development and feasibility testing for this device have already shown promising results in a previous phase.

Where this research is happening

Charlottesville, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.