A new flexible endoscope for quickly removing large kidney stones
Official title: Breaking the Scope Port Size Barrier: A New Kind of Endoscope that Removes Large Kidney Stones Rapidly
Funded at Endotheia, INC. · NIH-10896987 · Data updated 2026-11-12
This study is testing a new type of flexible tool that can quickly change from a camera used to look inside the body into a suction device that helps remove large kidney stones, making it easier and faster for patients to get treatment without needing major surgery.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Endotheia, INC. NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | August 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $919,117 |
| NIH project number | 5R44DK137695-02 |
| Project ID | NIH-10896987 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with large kidney stones who require intervention for stone removal.
✕Less likely to help
Patients with small kidney stones or those who do not require intervention may not benefit from this research.
What this research studies
This research aims to develop an innovative flexible ureteroscope that can quickly transform from an endoscope into a large-lumen suction catheter. This transformation allows for the rapid removal of large kidney stones, which can significantly reduce the need for invasive surgical procedures. The device is designed to decrease procedure times by at least 36 minutes, making it easier for patients with larger stones to undergo minimally invasive treatments. The approach utilizes a novel mechanical actuation concept that integrates bending capabilities directly into the device, enhancing its functionality.
Why it matters
Potential benefit: If successful, this research could lead to faster and less invasive treatments for patients suffering from large kidney stones.
How similar studies have gone: Other research has shown promise in developing advanced endoscopic techniques, but this specific approach is innovative and largely untested.
Where this research is happening
-
Endotheia, INC.
Nashville, United States Active
Researchers
- Principal investigator: Gafford, Joshua B — Endotheia, INC.
- Study coordinator: Gafford, Joshua B
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.