A new device to treat gastroesophageal reflux disease (GERD)

Clinical Feasibility Study of a Novel Flexible, Non-occlusive GERD Treatment Device

NIH-funded research Aplos Medical INC · NIH-10634514

This study is testing a new, easy-to-use device called the Ω-Cuff that helps people with gastroesophageal reflux disease (GERD) by reducing acid reflux without surgery that changes the esophagus, so you can feel better and rely less on medications.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionAplos Medical INC NIH-funded
Lab location1 site (Eden Prairie, United States)
Project IDNIH-10634514 on NIH RePORTER

What this research studies

This research focuses on developing a flexible, non-occlusive device called the Ω-Cuff to treat gastroesophageal reflux disease (GERD). GERD occurs when stomach acid frequently flows back into the esophagus, causing discomfort and potential serious health issues. The Ω-Cuff is designed to be implanted using a minimally invasive laparoscopic procedure, which avoids altering the anatomy of the esophagus. This device aims to reduce reliance on long-term medications and improve patient outcomes by providing a safer and more effective treatment option.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from gastroesophageal reflux disease who are seeking alternatives to medication or traditional surgical options.

Not a fit: Patients who do not have GERD or those who are not suitable candidates for surgical interventions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safer and more effective treatment for GERD, reducing the need for medications and improving quality of life for patients.

How similar studies have performed: Other research has shown success with similar minimally invasive approaches to treating GERD, indicating potential for this novel device.

Where this research is happening

Eden Prairie, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Barrett Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.