A new device to repair tears in the protective membrane around the brain and spine during surgery
Novel device for the repair and sealing of dural perforations in minimally invasive surgery
This study is testing a new tool that helps doctors quickly fix small holes in the protective layer around the brain and spine during minimally invasive surgeries, making it easier to prevent leaks and keep patients safe.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Patchclamp Medtech, INC. NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10818254 on NIH RePORTER |
What this research studies
This research focuses on developing a novel device designed to repair and seal perforations in the dura mater, the protective membrane surrounding the brain and spine, which can occur during minimally invasive surgeries. The device allows surgeons to quickly and effectively apply a graft to the damaged area using a single-hand applicator, which is particularly useful in the limited space of minimally invasive procedures. The research involves testing the device's effectiveness in laboratory settings and in live models to ensure it creates a secure, watertight seal, preventing complications from cerebrospinal fluid leakage.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing minimally invasive cranial or spinal surgeries who may be at risk for dural perforations.
Not a fit: Patients who are not undergoing surgery or those with conditions that do not involve dural perforations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of serious complications from dural perforations during surgery, leading to better patient outcomes and shorter recovery times.
How similar studies have performed: Other research has shown promise in developing similar devices for surgical applications, indicating a potential for success in this novel approach.
Where this research is happening
Seattle, United States
- Patchclamp Medtech, INC. — Seattle, United States (Active)
Researchers
- Principal investigator: Mayberg, Marc Robert — Patchclamp Medtech, INC.
- Study coordinator: Mayberg, Marc Robert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.