A new device to repair mitral valve leaks using a minimally invasive technique.
Novel Self-closing 12F Mitral Valve Repair System to Percutaneously Treat Moderate to Severe Regurgitation Using Transcatheter Edge-to-Edge Repair (TEER) Technique Via Femoral Vein Access.
This study is testing a new, easier-to-use device called the MEDFREE® Valve Repair System to help people with moderate to severe mitral valve regurgitation, making the treatment simpler for doctors and potentially better for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medfree, INC. NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-11059902 on NIH RePORTER |
What this research studies
This research focuses on developing the MEDFREE® Valve Repair System, which aims to enhance the current MitraClip device for treating moderate to severe mitral valve regurgitation. The approach utilizes a smaller 12F catheter system that allows for a single operator to perform the procedure, making it simpler and more efficient. The research has already shown promising results in preclinical studies using animal models, and it is now preparing for early-phase clinical studies to evaluate its effectiveness in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with moderate to severe mitral valve regurgitation who are seeking less invasive treatment options.
Not a fit: Patients with mild mitral valve regurgitation or those who are not candidates for any form of valve repair may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a less invasive and more effective treatment option for patients suffering from mitral valve regurgitation.
How similar studies have performed: Previous research with similar transcatheter techniques has shown success, indicating a promising outlook for this novel approach.
Where this research is happening
Newark, UNITED STATES
- Medfree, INC. — Newark, United States (Active)
Researchers
- Principal investigator: Basude, Raghuveer — Medfree, INC.
- Study coordinator: Basude, Raghuveer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.