A new device to quickly diagnose sickle cell disease
Point of care diagnostic for sickle cell disease
This study is working on a handy device that helps doctors quickly check the health of red blood cells in people with sickle cell disease, so they can better manage their condition and predict painful episodes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11179696 on NIH RePORTER |
What this research studies
This research aims to develop a point-of-care diagnostic device for sickle cell disease (SCD) that can quickly assess the health of red blood cells (RBCs) in patients. By using advanced imaging technology and machine learning algorithms, the device will analyze RBC samples to identify sickled cells and predict the likelihood of painful vaso-occlusive crises. This approach allows for real-time monitoring of patients, potentially improving their management and treatment options. The goal is to create a user-friendly tool that can be used in various healthcare settings, especially in regions heavily affected by SCD.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns and young children diagnosed with sickle cell disease, particularly those from African American or Sub-Saharan African backgrounds.
Not a fit: Patients who do not have sickle cell disease or those who are not within the targeted age group may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management of sickle cell disease, reducing pain crises and improving the quality of life for patients.
How similar studies have performed: Other research has shown promise in using advanced imaging and AI for diagnosing blood disorders, indicating that this approach could be effective.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Wax, Adam — Duke University
- Study coordinator: Wax, Adam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.