A new device to improve treatment for blocked coronary arteries
Official title: Magnetic Rotational Platform for Coronary Lesions
Funded at Unandup, LLC · NIH-11077590 · Data updated 2026-11-12
This study is testing a new magnetic device that helps doctors treat tough blockages in heart arteries more effectively, making it easier to perform heart procedures and hopefully leading to better results for patients.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Unandup, LLC NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | April 20, 2025 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $413,595 |
| NIH project number | 1R43HL178364-01 |
| Project ID | NIH-11077590 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults suffering from coronary artery disease, particularly those with severely calcified lesions that have not responded well to standard treatments.
✕Less likely to help
Patients with non-cardiovascular conditions or those who do not have significant coronary artery blockages may not benefit from this research.
What this research studies
This research focuses on developing a magnetic rotational platform designed to enhance the treatment of coronary lesions, which are blockages in the arteries that supply blood to the heart. The approach aims to improve the effectiveness of percutaneous coronary interventions (PCI) by using advanced technology to navigate complex vascular pathways and treat severely calcified lesions that are difficult to address with current methods. By utilizing a magnetic system, the device seeks to provide better access and control during procedures, potentially leading to improved patient outcomes. The research will involve testing the device's performance in a controlled setting to ensure its safety and efficacy.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with severe coronary artery blockages, reducing the risk of heart attacks and improving overall heart health.
How similar studies have gone: Previous studies have shown that advanced atherectomy techniques can improve outcomes in patients with complex coronary lesions, indicating a promising avenue for this novel approach.
Where this research is happening
-
Unandup, LLC
Saint Louis, United States Active
Researchers
- Principal investigator: Creighton, Francis Milton — Unandup, LLC
- Study coordinator: Creighton, Francis Milton
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.