NIH-funded research Sbir 2 grant

A new device to improve inhaled drug delivery for pulmonary hypertension

Official title: Novel Device to Optimize Aerosol Drug Delivery for Pulmonary Hypertension Treatment

Funded at Bridgesource Medical Corporation · NIH-10912642 · Data updated 2026-11-12

This study is testing a new nebulizer that changes how it delivers medicine based on how you breathe, making it easier for people with pulmonary hypertension, especially older adults, to get their treatments and feel better.

More Hypertension research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionBridgesource Medical Corporation
NIH-funded
Lab location1 site (Austin, United States)
Project startAugust 1, 2020
Project endAugust 31, 2025
Funding year2024
Award (this year)$875,246
NIH project number5R44HL154960-03
Project IDNIH-10912642 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients with pulmonary hypertension, particularly elderly individuals who struggle with traditional inhalation therapies.

Less likely to help

Patients with mild respiratory conditions or those who do not require aerosolized medication may not benefit from this research.

What this research studies

This research focuses on developing a breath-adaptive nebulizer that can deliver aerosolized medications more effectively for patients with pulmonary hypertension. The device will adjust the size of aerosol droplets and the timing of drug delivery based on the patient's breathing patterns, making it easier for patients, especially the elderly, to receive their medications. By improving the efficiency of drug delivery, this device aims to enhance treatment compliance and outcomes for individuals with respiratory conditions. The ultimate goal is to create a device that can be approved by the FDA for clinical use.

Why it matters

Potential benefit: If successful, this research could lead to a more effective and user-friendly method of delivering medications for patients with pulmonary hypertension.

How similar studies have gone: Other research has shown promise in improving aerosol delivery systems, but this specific approach with a breath-adaptive nebulizer is relatively novel.

Where this research is happening

  • Bridgesource Medical Corporation
    Austin, United States
    Active

Researchers

  • Principal investigator: Porterfield, John E — Bridgesource Medical Corporation
  • Study coordinator: Porterfield, John E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.