A new device to improve endoscopic procedures in the upper gastrointestinal tract
Official title: Balloon Overtube Access Device for Improved Interventional Endoscopy in the Upper GI
Funded at Aspero Medical, INC. · NIH-10919076 · Data updated 2026-11-12
This study is testing a new flexible balloon device that helps doctors safely and effectively remove cancerous and precancerous growths from the upper digestive tract, making the procedure easier and better for patients.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Aspero Medical, INC. NIH-funded |
| Lab location | 1 site (Boulder, United States) |
| Project start | July 15, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,024,810 |
| NIH project number | 1R44DK136377-01A1 |
| Project ID | NIH-10919076 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with cancerous or precancerous lesions in the esophagus or stomach who may benefit from advanced endoscopic procedures.
✕Less likely to help
Patients with lesions that are not suitable for endoscopic intervention or those who are not candidates for ESD may not benefit from this research.
What this research studies
This research focuses on developing a flexible balloon overtube access device (BOAD) aimed at enhancing the safety and effectiveness of endoscopic submucosal dissection (ESD) for removing cancerous and precancerous lesions in the upper GI tract. The device is designed to facilitate the adoption of ESD, which has shown superior outcomes compared to traditional endoscopic mucosal resection (EMR). By addressing the technical challenges and risks associated with ESD, this innovative approach seeks to improve patient care and outcomes. The project includes preclinical testing and aims for FDA clearance to ensure the device meets safety and efficacy standards.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for patients with cancerous and precancerous lesions in the upper gastrointestinal tract.
How similar studies have gone: Previous research has shown promising results with similar devices aimed at improving endoscopic techniques, indicating a potential for success in this novel approach.
Where this research is happening
-
Aspero Medical, INC.
Boulder, United States Active
Researchers
- Principal investigator: Rentschler, Mark — Aspero Medical, INC.
- Study coordinator: Rentschler, Mark
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.