A new contraceptive vaginal film that uses a human contraceptive antibody.
Project 2: Phase 1 and Phase 2a ZB-06 Clinical Studies
This study is testing a new, easy-to-use vaginal film that women can insert before sex to help prevent pregnancy, and it's designed to be safe and effective without hormones.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10923983 on NIH RePORTER |
What this research studies
This research investigates a non-hormonal, female-controlled contraceptive vaginal film that releases a human contraceptive antibody (HCA). The film is designed to be used on-demand, inserted prior to unprotected intercourse, and aims to provide an effective contraceptive option for women. The study will involve clinical trials to assess the safety, pharmacokinetics, and contraceptive efficacy of the film, with initial results indicating it is safe and effective in reducing sperm motility. Participants will be monitored for their experiences and outcomes during the trials.
Who could benefit from this research
Good fit: Ideal candidates for participation are women of reproductive age who are seeking a non-hormonal contraceptive method.
Not a fit: Patients who are not sexually active or those who are not seeking contraceptive options may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide women with a new, effective contraceptive option that is under their control.
How similar studies have performed: Similar research has shown promise in developing non-hormonal contraceptive methods, but this specific approach is novel.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Thurman, Andrea Ries — Boston University Medical Campus
- Study coordinator: Thurman, Andrea Ries
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.