A new collagen scaffold for repairing large rotator cuff tears

OsTend: A load-bearing, bi-phasic collagen scaffold for massive rotator cuff repairs

NIH-funded research Collamedix INC. · NIH-10761321

This study is testing a special collagen patch designed to help heal severe rotator cuff tears for people who might not benefit from regular surgery, aiming to make recovery easier and more effective.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionCollamedix INC. NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-10761321 on NIH RePORTER

What this research studies

This research focuses on developing a bi-phasic collagen scaffold designed to aid in the repair of massive rotator cuff tears, which are often too severe for traditional surgical methods. The scaffold is made from high-strength pure-collagen threads that are engineered to mimic the natural structure of tendon tissue, promoting healing and regeneration. By using a patented process, the scaffold is created to be biocompatible and resorbable, allowing for better integration with the patient's own tissue. The goal is to provide a more effective solution for patients suffering from irreparable rotator cuff injuries, potentially reducing the need for more invasive procedures.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with massive rotator cuff tears that cannot be repaired using standard arthroscopic techniques.

Not a fit: Patients with minor rotator cuff injuries or those who do not require surgical intervention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve recovery outcomes for patients with massive rotator cuff tears, reducing pain and disability.

How similar studies have performed: Other research has shown promise in using biocompatible scaffolds for tissue regeneration, indicating that this approach could be effective.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.