A new cell-based therapy for complex regional pain syndrome
A first in class, mechanism-guided, cell-based therapy for complex regional pain syndrome
This study is exploring a new way to help adults with complex regional pain syndrome (CRPS) by using special cells from the body to reduce pain and improve daily activities, and it aims to get ready for testing this treatment in patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10572041 on NIH RePORTER |
What this research studies
This research focuses on developing a novel treatment for complex regional pain syndrome (CRPS), a debilitating chronic pain condition affecting many adults. The approach involves using human mesenchymal stem cells (hMSCs) derived from various tissues, including bone marrow and adipose tissue, to alleviate pain and improve function. The study aims to optimize treatment protocols and gain approval for clinical trials to test the safety and effectiveness of this therapy in patients suffering from CRPS.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are diagnosed with complex regional pain syndrome.
Not a fit: Patients with chronic pain conditions other than complex regional pain syndrome may not benefit from this specific research.
Why it matters
Potential benefit: If successful, this research could provide a groundbreaking treatment option that significantly reduces pain and improves quality of life for patients with CRPS.
How similar studies have performed: Other research has shown promise in using stem cell therapies for pain management, indicating potential success for this novel approach.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Cheng, Jianguo — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Cheng, Jianguo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.