A new catheter to treat ventricular tachycardia
Official title: Eliminating Ventricular Tachycardia: Pivotal Clinical Trial using the Durablate® Catheter
Funded at Thermedical, INC. · NIH-10928202 · Data updated 2026-11-12
This study is testing a new catheter called Durablate® that aims to help people with ventricular tachycardia (VT) by using heat and special imaging to treat the heart more effectively and gently than current options.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thermedical, INC. NIH-funded |
| Lab location | 1 site (Waltham, United States) |
| Project start | September 12, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,210,431 |
| NIH project number | 5R44HL169112-02 |
| Project ID | NIH-10928202 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with ventricular tachycardia who may benefit from a more effective treatment option.
✕Less likely to help
Patients with other types of arrhythmias or those who do not have ventricular tachycardia may not benefit from this research.
What this research studies
This research focuses on developing the Durablate® Catheter, a novel tool designed to treat ventricular tachycardia (VT), a serious heart condition that can lead to sudden cardiac death. The study aims to improve upon existing treatments, such as implantable cardioverter defibrillators (ICDs), which are costly and not curative. By utilizing advanced imaging techniques and a unique method of delivering heated saline with radiofrequency energy, the catheter targets and ablates the heart tissue responsible for VT. This approach seeks to provide a more effective and less traumatic solution for patients suffering from this condition.
Why it matters
Potential benefit: If successful, this research could significantly reduce the need for expensive ICDs and improve the quality of life for patients with ventricular tachycardia.
How similar studies have gone: Previous research has shown promise in using ablation techniques for treating arrhythmias, but this specific approach with the Durablate® Catheter is novel.
Where this research is happening
-
Thermedical, INC.
Waltham, United States Active
Researchers
- Principal investigator: Curley, Michael G — Thermedical, INC.
- Study coordinator: Curley, Michael G
Related research
Other NIH-funded projects on the same topics.
-
Map heart tissue to guide VT ablation with AI help
A patient-oriented project aims to use AI-based mapping to better identify abnormal heart tissue responsible for ventricular tachycardia and guide safer, faster ablation.
-
Proton SBRT for refractory ventricular tachycardia with real-time 3D/4D imaging
A patient-facing study exploring a proton-based, noninvasive radiation therapy to treat stubborn VT using advanced 3D and 4D imaging to target the heart safely.
-
Venous ethanol ablation to treat ischemic VT (VE-VT)
A new treatment approach uses ethanol delivered through heart veins to help stop dangerous heart rhythms in patients with previous heart damage.
-
Novel gene therapy tools to prevent dangerous heart rhythms
A small grant supports testing gene-therapy methods to stop ventricular tachycardia after a heart attack, with the goal of helping people at risk of sudden heart rhythm problems.
-
Radiation-guided ablation for ventricular tachycardia
This project tests a noninvasive radiation approach to ablate heart tissue in people with dangerous ventricular tachycardia to reduce the need for invasive procedures.
-
Low-Field MRI–Guided Robotic Catheter System for VT Ablation
A research project is testing a new low-field MRI–guided robotic catheter to improve treatment of ventricular tachycardia for patients with abnormal heart structure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.