NIH-funded research Sbir 2 grant

A New Brain Wave Test for Alzheimer's Disease and Memory Problems

Official title: Validation of a novel EEG-based neurodiagnostic platform for assessing cognitive impairment and Alzheimer's Disease

Funded at Spark Neuro INC. · NIH-11158644 · Data updated 2026-11-12

This project is developing a new, easy brain wave test to help identify people who might have Alzheimer's disease or other memory issues.

More s Disease research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionSpark Neuro INC.
NIH-funded
Lab location1 site (New York, UNITED STATES)
Project startSeptember 15, 2022
Project endApril 30, 2027
Funding year2025
Award (this year)$1,161,079
NIH project number5R44AG078039-03
Project IDNIH-11158644 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this type of research would be individuals experiencing memory concerns or cognitive impairment who might be candidates for Alzheimer's disease biomarker testing.

Less likely to help

Patients without cognitive impairment or those not seeking a diagnosis for memory issues would likely not directly benefit from this specific diagnostic tool.

What this research studies

Alzheimer's disease diagnosis often requires complex tests, and this project aims to make that process simpler and more accessible. We are working on a new tool called SPARK Scan, which uses brain wave measurements (EEG) to detect and stage memory problems. This non-invasive and cost-effective test could help doctors decide who needs further specialized testing for Alzheimer's. The current phase involves a large clinical study to confirm how well this new test works.

Why it matters

Potential benefit: If successful, this new brain wave test could lead to earlier and more accurate identification of Alzheimer's disease, allowing patients to access treatments sooner.

How similar studies have gone: This project builds upon successful findings from an earlier phase, suggesting promising initial results for the technology.

Where this research is happening

  • Spark Neuro INC.
    New York, United States
    Active

Researchers

  • Principal investigator: Yoder, Keith — Spark Neuro INC.
  • Study coordinator: Yoder, Keith

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.