A new blood test to track ovarian cancer
Nano-CRISPR extracellular vesicle sensing system for longitudinal tumor monitoring
This project aims to create a new blood test to track how ovarian cancer responds to treatment and if it becomes resistant to drugs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11141816 on NIH RePORTER |
What this research studies
Ovarian cancer can be hard to monitor, especially to see if treatments are working or if the cancer is becoming resistant. This project focuses on tiny particles called extracellular vesicles (EVs) found in your blood, which carry information about your tumor. Researchers are developing a new technology called nano-CRISPR to detect these EVs more accurately and easily. This advanced system will help doctors get a clearer picture of your cancer's status without needing invasive procedures, offering a molecular 'snapshot' of the tumor.
Who could benefit from this research
Good fit: This research is relevant for patients with ovarian cancer, particularly those undergoing treatment who need better ways to monitor their disease.
Not a fit: Patients without ovarian cancer or those not seeking advanced monitoring for their condition would not directly benefit from this specific technology.
Why it matters
Potential benefit: If successful, this technology could provide a non-invasive and real-time way for doctors to track ovarian cancer, helping them make better treatment decisions.
How similar studies have performed: While the concept of using EVs for cancer monitoring is promising, this specific nano-CRISPR system represents a novel approach to improve sensitivity and standardization.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Im, Hyungsoon — Massachusetts General Hospital
- Study coordinator: Im, Hyungsoon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.