A new blood test to detect active tuberculosis disease.
Detecting active tuberculosis disease: a blood-based Mycobacterium tuberculosis antigen detection asssay
This study is working on a quick and reliable blood test to help diagnose active tuberculosis (TB) in people living with HIV, making it easier to find and treat the disease sooner.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11112439 on NIH RePORTER |
What this research studies
This research focuses on developing a rapid and accurate blood-based test to diagnose active tuberculosis (TB) disease, particularly in individuals living with HIV. Current diagnostic methods are often sputum-based and may not effectively identify TB in patients with less common forms of the disease. By detecting a specific antigen associated with Mycobacterium tuberculosis in blood samples, the study aims to provide a more accessible and sensitive diagnostic tool. This could significantly reduce delays in treatment and improve health outcomes for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who may be at risk for active tuberculosis disease.
Not a fit: Patients who do not have HIV or are not at risk for tuberculosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more effective and timely diagnosis of tuberculosis, particularly for those living with HIV.
How similar studies have performed: While there have been advancements in diagnostic methods for tuberculosis, this specific approach using blood-based antigen detection is relatively novel and untested.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Seifert, Marva — University of California, San Diego
- Study coordinator: Seifert, Marva
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.