A new biodegradable implant to prevent HIV infection
Acceptable Multi-user Biodegradable Extended Release (AMBER) Implant System for HIV Prevention
['FUNDING_R01'] · RESEARCH TRIANGLE INSTITUTE · NIH-10907450
This study is working on a new, easy-to-use implant that helps protect against HIV for up to a year without the need for daily pills, and it can be safely removed if needed, with input from different communities to make sure it fits everyone's needs.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RESEARCH TRIANGLE INSTITUTE (nih funded) |
| Locations | 1 site (RESEARCH TRIANGLE PARK, UNITED STATES) |
| Trial ID | NIH-10907450 on ClinicalTrials.gov |
What this research studies
This research aims to create an innovative implant for HIV pre-exposure prophylaxis (PrEP) that is user-friendly and discreet. The AMBER implant will provide long-term protection for up to a year, releasing medication steadily without requiring daily adherence. It is designed to be retrievable in case of adverse reactions or if the user decides to stop using it. The development process will involve gathering insights from diverse populations to ensure the implant meets the needs of various communities.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at high risk for HIV who are seeking effective prevention methods.
Not a fit: Patients who are not at risk for HIV or those who prefer traditional daily medication may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more effective and convenient method for preventing HIV infection.
How similar studies have performed: Other research has shown promise in developing long-acting HIV prevention methods, but this biodegradable implant represents a novel approach.
Where this research is happening
RESEARCH TRIANGLE PARK, UNITED STATES
- RESEARCH TRIANGLE INSTITUTE — RESEARCH TRIANGLE PARK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JOHNSON, LEAH — RESEARCH TRIANGLE INSTITUTE
- Study coordinator: JOHNSON, LEAH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus